In vitro studies of the interactions between platelets and amniotic membranes: a potential treatment for preterm premature rupture of the membranes

Article Abstract:

Blood platelets may effectively seal punctures in fetal membranes. Premature rupture of fetal membranes rapidly leads to delivery and, therefore, a premature infant. A technique to patch ruptured fetal membranes may permit a pregnancy to continue, improving the outcome for the baby. Researchers experimented with fresh fetal membranes, amniotic fluid, and platelets obtained from a blood bank. Fetal membrane connective tissue, as would be exposed in a rupture, caused platelet activation and the formation of a platelet plug. This may form the basis of a membrane repair.

Premature rupture of membranes, Premature rupture of the membrane, Blood platelets

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Multifetal pregnancy reduction is not associated with an increased risk of intrauterine growth restriction, except for very-high-order multiples

Article Abstract:

In vitro fertilization that results in five or more embryos appears to increase the risk of intrauterine growth restriction (IUGR) even if the pregnancy is reduced to two fetuses. Researchers analyzed the rates of IUGR in 441 women with twin pregnancies after undergoing multifetal pregnancy reduction and 136 women with natural twin pregnancies. No differences were found in the rate of IUGR except in the women who had five or more fetuses before the reduction procedure. These women had twice the risk of IUGR.

Fetus, Fetal growth retardation, Growth disorders, Pregnancy, Multiple, Multiple pregnancy

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Perinatal outcome in grand and great-grand multiparity: effects of parity on obstetric risk factors

Article Abstract:

Women who have more than 10 children may have a greater risk of childbirth complications. However, the infant death rate is low, so having more than 10 children is not necessarily dangerous provided the mother receives adequate prenatal care.

Pregnancy, Complications of, Pregnancy complications, Family size

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