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Influence of peak viral load on the extent of CD4(super +) T-cell depletion in Simian HIV infection

Article Abstract:

Simian HIV infection of macaques with CXCR4 tropic viruses results in early and profound CD4(super +) T-cell depletion in the first few weeks of infection. The dynamics of the interaction of virus and CD4(super +) cells are modeled over time to investigate the rate of CD4(super -) T-cell infection and death and it is indicated that the proportion of CD4(super -) cells destroyed is correlated with the peak viral load.

Author: Perelson, Alan S., Ribeiro, Ruy M., Lei Zhang, Shiver, John W., Davenport, Miles P., Casmiro, Danilo R.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
Health aspects, HIV infection, HIV infections, CD4 lymphocytes, Simian immunodeficiency virus

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Interferon [gamma]-inducible protein 10 A predictive marker of successful treatment response in hepatitis C virus/HIV-coinfected patients

Article Abstract:

Inducible protein (IP)-10 is a marker of treatment outcome in hepatitis C virus (HCV)/HIV-coinfected patients are determined. It is concluded that IP-10 is a biomarker of HCV treatment outcome in difficult-to-treat HCV/HIV-coinfected patients.

Author: Talal, Andrew H., Markatou, Marianthi, Dorante, Gary, Zeremski, Marija, Brown, Queenie B., Cunningham-Rundles, Susanna
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007

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Virus dynamics and immune responses during treatment in patients coinfected with hepatitis C and HIV

Article Abstract:

The infection of the Hepatitis C virus (HCV) on human body, which can cause death, is described. The mathematical model to calculate half lives of the virus and HCV-infected cells in HIV-HCV-coinfected patients are discussed.

Author: Talal, Andrew H., Perelson, Alan S., Ribeiro, Ruy M., Chadburn, Amy, Shata, M. Tarek, Markatou, Marianthi, Dorante, Gary, Koch, Robert, Neumann, Avidan U.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2004
HIV (Viruses), HIV, Hepatitis C

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Subjects list: Research, Risk factors, Care and treatment, HIV patients, Hepatitis C virus
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