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Insulin lispro

Article Abstract:

Some diabetics may benefit from an insulin analogue called lispro. Lispro was developed to make a type of insulin that could be injected several times a day to maintain good glucose control. This could reduce the risk of diabetic complications. Lispro may be better absorbed after subcutaneous injections and acts more quickly than regular insulin. Thus, it must be injected immediately before a meal. It may be easier for diabetics to remember this and many may enjoy the convenience. Lispro reduces the risk of hypoglycemia somewhat and appears to be no more immunogenic that regular insulin.

Author: Holleman, Frits, Hoekstra, Joost B.L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Drug therapy, Insulin, Insulin derivatives

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Insulin-like growth factors

Article Abstract:

Insulin-like growth factors (IGFs) appear to be promising therapeutic agents for many metabolic disorders but their exact function needs to be determined. There are two IGFs, IGF-I and IGF-II, and they are similar in structure to insulin. However, they are produced by the liver and other tissues. IGF-I is produced by the interaction of growth hormone with its receptor and appears to be responsible for many of the activities associated with this hormone. It may be a useful therapeutic agent for osteoporosis, diabetes, obesity, growth deficiency and insulin resistance.

Author: Le Roith, Derek
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Care and treatment, Physiological aspects, Growth disorders, Insulin-like growth factors, Somatomedins

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Subjects list: Diabetes, Diabetes mellitus
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