Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia

Article Abstract:

Increased levels of interleukin-6 may be found in the blood of newborns with periventricular leukomalacia lesions. Such lesions contribute to cerebral palsy, and consist of dead tissue in the white matter of the brain. Researchers analyzed umbilical cord blood samples from 172 preterm infants, as preterm infants have an increased risk of cerebral palsy. Brain ultrasound examinations diagnosed periventricular leukomalacia lesions in 25 of the infants (14.5%) before their third day of life. Elevated interleukin-6 levels were associated with the presence of periventricular leukomalacia lesions. This finding may suggest that fetal infection may trigger an inflammatory response which results in damage to brain white matter. Fetal infection may also trigger preterm birth.

Measurement, Brain, Interleukin-6, Abscess, Brain abscess

---

Clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes

Article Abstract:

The frequency and clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes was studied. Results revealed that intra-amniotic inflammation was present in 42% of patients and it is a risk factor for impending preterm delivery and adverse outcome.

United States, Causes of, Infants (Newborn), Premature rupture of membranes, Premature rupture of the membrane, Premature birth, Neonatal diseases

---

Similar abstracts:

• Abstracts: Antenatal microbiologic and maternal risk factors associated with prematurity. part 2 Chlamydia trachomatis infection during pregnancy
• Abstracts: Clinical aspects of the relationship between oral contraceptives, abnormalities in carbohydrate metabolism, and the development of cardiovascular disease
• Abstracts: Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy
• Abstracts: A systemic fetal inflammatory response and the development of bronchopulmonary dysplasia. The relationship between amniotic fluid matrix metalloproteinase-8 and funisitis

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.