Investigation of anal function in patients with systemic sclerosis

Article Abstract:

Patients with systemic sclerosis (SSc) may have defective anal muscle function. Researchers evaluated various measures of anal muscle function in 16 SSc patients and 11 healthy volunteers. Six SSc patients had no bowel function abnormalities, seven had constipation, and three had diarrhea and stool incontinence. Anal muscle function deviated most from the norms of the healthy patients among SSc patients experiencing bowel function abnormalities. However, even symptom-free patients tended to have abnormal pressure values compared with healthy persons.

Measurement, Causes of, Muscle strength, Fecal incontinence

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Clinical significance of subcutaneous calcinosis in patients with systemic sclerosis. Does diltiazem induce its regression?

Article Abstract:

Diltiazem may not be an effective treatment for subcutaneous calcinosis (SCC) in patients with systemic sclerosis. Systemic sclerosis is an autoimmune disease, and often leads to the deposition of calcium under the skin. Researchers evaluated diltiazem in 47 patients with systemic sclerosis. Of the 12 patients who also had SCC, diltiazem produced only a slight improvement in the calcium deposits in three patients. Patients with SCC and systemic sclerosis had distinctive immune changes and more damage to capillaries in the skin.

Evaluation, Calcium in the body, Calcium (Nutrient), Diltiazem

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A prospective evaluation of central venous blood flow using Doppler ultrasound in patients with a long term central venous catheter

Article Abstract:

The correlation between blood flow characteristics and the development of central venous thrombosis in 10 patients requiring long term central venous catheterization are studied using Doppler ultrasound. Results show that an intravascular foreign body will not affect blood flow characteristics in the upper body veins. Turbulent blood flow is also not a determinant of the development of intravascular thrombus.

Research, Blood flow, Thrombosis, Intravenous catheterization

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