Isolation and transduction of CD34+ cells from small quantities of peripheral blood from HIV-1-infected patients not treated with hemopoietic growth factors

Article Abstract:

It may be possible to isolate CD34+ T cells from the blood of HIV patients without giving them hemopoietic growth factors. These growth factors are used to boost the production of T cells. Researchers measured the amount of CD34+ T cells in blood samples from HIV-negative volunteers and HIV-positive patients, some of whom received growth factors and some of whom did not. Although the HIV-positive patients not taking growth factors had lower levels of T cells than the HIV-negative volunteers, the number of cells was still adequate. The cells will be used to administer gene therapy to HIV patients.

Usage, Measurement, HIV patients, Gene therapy, Growth factors

---

Active movement of T cells away from a chemokine

Article Abstract:

Researchers show that T cells can move away from a stimulus just as neurons, prokaryotes, and simple eukaryotes. High concentrations of the chemokine stromal cell derived factor-1 repelled T cells, a movement that was inhibited by antibody against the CXCR4 receptor.

Cells, Cell migration, Cytokines

---

The lysophosphatidic acid receptor [LPA.sub.1] links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

Article Abstract:

The function of the lysophosphatidic acid receptor [LPA.sub.1] in mediating fibroblast recruitment and vascular leak that allows lung injury to lead to pulmonary fibrosis is discussed.

Science & research, G proteins, Fibroblasts, Leukocytes, White blood cells, Pulmonary fibrosis

Similar abstracts:

• Abstracts: Amputation: the transition from hospital to home. Assertive outreach: a step backwards. Is there such a thing as a personality disorder?
• Abstracts: Twins and triplets: The effect of plurality and growth on neonatal outcome compared with singleton infants. Appendicitis in pregnancy: new information that contradicts long-held clinical beliefs
• Abstracts: The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. E. coli, antibiotics, and the hemolytic-uremic syndrome
• Abstracts: Chromosome 5q deletion and epigenetic suppression of the gene encoding [alpha]-catenin (CTNNA1) in myeloid cell transformation

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.