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Viral load and heterosexual transmission of human immunodeficiency virus type 1

Article Abstract:

HIV patients with fewer than 1,500 copies of HIV-1 per milliliter of blood will probably not transmit the virus through sexual intercourse. This was the conclusion of researchers who analyzed transmission rates in 415 couples in which one partner was HIV-positive. Of the 415 HIV-negative partners, 90 became HIV-positive over a 30-month period. The rate of male-to-female transmission was approximately equal to the rate of female-to-male transmission. None of the 51 people with low viral counts transmitted the virus. Increasing levels of virus caused an increasing risk of transmission.

Author: Quinn, Thomas C., Wawer, Maria J., Sewankambo, Nelson, Serwadda, David, Li, Chuanjun, Wabwire-Mangen, Fred, Meehan, Mary O., Lutalo, Thomas, Gray, Ronald H.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Health aspects, Viremia

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Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda

Article Abstract:

Treating HIV-infected pregnant women for a sexually transmitted disease can reduce the rate of neonatal death, premature birth, and low birth weight but does not reduce the risk of transmitting the virus to the baby. This was the conclusion of a study of 2,070 pregnant women in Uganda.

Author: Quinn, Thomas C., Wawer, Maria J., Serwadda, David, Wabwire-Mangen, Fred, Gray, Ronald H., Abramowsky, Carlos, Meehan, Mary, Kigozi, Godfrey, Sewankambo, Nelson K., Moulton, Lawrence H., O'Brien, Katherine L., Robb, Merlin
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
Sexually transmitted diseases, Care and treatment, HIV infections, Pregnancy, HIV infection in pregnancy

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Knowledge about vaccines and willingness to participate in preventive HIV vaccine trials: a population-based study, Rakai, Uganda

Article Abstract:

A survey was conducted among 14,177 participants in the age group of 15 to 49 years to assess knowledge regarding vaccines and the willingness to participate in HIV vaccine trials in Uganda. The knowledge of vaccines in this population was 71%, and 77% of the participants were willing to participate in preventive trials.

Author: Wawer, Maria J., Serwadda, David, Wabwire-Mangen, Fred, Gray, Ronald H., Phillips, James, Kigozi, Godfrey, Sewankambo, Nelson K., Robb, Merlin, Birx, Deborah, Kiwanuka, Noah, Nalugoda, Fred
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2004
Science & research, Analysis, AIDS (Disease), AIDS vaccines, Health surveys, AIDS research

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Subjects list: HIV (Viruses), HIV, Disease transmission, Research
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