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Local dystrophin restoration with antisense oligonucleotide PRO051

Article Abstract:

A study to assess the benefits if any to patients afflicted with Duchenne's muscular dystrophy who were administered antisense oligonucleotide PRO051 is conducted. Results show positive benefits among patients who received the intramuscular dose leaving scope for further studies.

Author: van Deutekom, Judith C., Janson, Anneke A., Ginjaar, Ieke B., Frankhuizen, Wendy S., Aartsma-Rus, Annemieke, Bremmer-Bout, Mattie, der Dunner, Johan T., Koop, Klaas, van der Kooi, Anneke J., Goemans, Nathalie M., de Kimpe, Sjef J., Ekhart, Peter F., Venneker, Edna H., Platenburg, Gerard J., Verschuuren, Jan J., van Ommen, Gert-Jan B.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Nucleic Acid Derivatives, Nucleotides, Dystrophin, Clinical report

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A hot spot of genetic instability in autism

Article Abstract:

Autism, the neurobehavioral syndrome and the ongoing research to try and establish methods for solution is discussed. Some of the different studies are discussed to try and understand the genomic contributors to autism.

Author: Eichler, Evan E., Zimmerman, Andrew W.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2008
Psychological aspects, Editorial, Autism, Genomics

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Skipping toward personalized molecular medicine

Article Abstract:

The use of a new concept 'Personalized molecular medicine' to find the individualized line of treatment in medical cases is discussed.

Author: Hoffman, Eric P.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Drugs, Nucleic Acids

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Subjects list: Health aspects, Research, United States, Drug therapy, Genetic aspects, Mutation (Biology), Mutation, Duchenne muscular dystrophy
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