Lupus "gatekeeper" gene discovered

Article Abstract:

Findings reveal that the restoration of the levels of receptors coded by a single 'gatekeeper' gene could halt the development of lupus in mice. An inhibitory Fc receptor that plays a critical role in the ability of the immune system to distinguish between self and nonself in the mouse was identified, and found that even partial restoration of the receptor's function prevented the development of lupus in several lupus-prone mouse strains.

Lupus, Genetic research

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Scientists seek cause of drug craving

Article Abstract:

Repeated administration of psychoactive drugs such as cocaine and amphetamine and corresponding reduction in glutamate mediated communication between glutamate receptors and cell signaling in the nucleus accumbens play a role in drug-craving. A study on a rat model suggested that a reduced number of glutamate receptors in the nucleus accumbens caused by repeated drug exposure account for drug-craving behavior.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Psychotherapeutic Preparations, Glutamate, Drug abuse, Psychotropic drugs

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Nobels honor research on ulcer microbe, "Green" drug production method

Article Abstract:

The 2005 Nobel Prize in Physiology or Medicine is awarded to a pair of Australian researchers, Barry J. Marshall, MBBS and J. Robin Warren, MBBS, whose work revolutionized how peptic ulcers are treated. The 2005 Nobel Prize in Chemistry went to trio of chemists who developed a technique for manufacturing pharmaceuticals, plastics and other products that produces less waste.

Achievements and awards, Peptic ulcer, Medical research personnel, Medical researchers, Marshall, Barry, Warren, J. Robin

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