Management strategies for Helicobacter pylori-seropositive patients with dyspepsia: clinical and economic consequences

Article Abstract:

It appears that immediate treatment for suspected Helicobacter (H.) pylori infections based on blood tests and patient characteristics is a cost-effective strategy. Researchers used a statistical model to evaluate treatment decisions for patients who have a positive H. pylori blood test and indigestion. Immediate antibiotic treatment resulted in a $456 per patient cost savings compared to more invasive but conclusive screening tests. Doctors would have to perform substantially fewer invasive tests to balance cost-effectiveness. Potential drug resistance or ineffectiveness may be reasons for not following this strategy.

Research, Cost benefit analysis

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Helicobacter pylori: when to test, when to treat

Article Abstract:

Evidence suggests that prompt treatment for Helicobacter (H.) pylori infections may be advisable. Hypothetical cost analyses have shown that routine invasive tests done to conclusively determine whether patients have H. pylori infections are significantly more expensive than prompt treatment for patients with positive blood or breath tests. Future research should address finding the most effective treatment approach to reduce pain associated with H. pylori-associated abdominal pain. Patients with ulcers or severe indigestion may be candidates for testing and treatment.

Editorial, Testing, Helicobacter pylori

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Combination therapies commonly used for stomach ulcers are probably not useful for treating stomach discomfort

Article Abstract:

Treating Helicobacter pylori infection may not be beneficial for patients with indigestion but no stomach ulcer. Helicobacter pylori is a bacterium that has been linked to stomach ulcers but doctors don't know whether it can cause indigestion.

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