Localization of p43 placental isoferritin in human maternal-fetal tissue interface

Article Abstract:

The p43 subunit of placental isoferritin may suppress a pregnant woman's immune response toward her baby. This subunit was found in placental tissues and fetal membranes in a study of 50 women .

Immunosuppression

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Maternal circulation in the first-trimester human placenta - myth or reality?

Article Abstract:

Maternal blood may not enter and circulate within the placenta until the end of the first trimester of pregnancy. The standing theory of placental development states that maternal blood enters the early placenta near the beginning of pregnancy. Recent research reveals that plugs of tissue block maternal blood flow into the early placenta. These plugs do not become loose until near the end of the first trimester of human pregnancy. The embryo may prefer to grow in a low oxygen environment, which would support the theory that maternal blood is blocked until the second trimester.

Uterine circulation

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Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd Collection revisited

Article Abstract:

The maternal blood circulation to the placenta does not become established until the 11th or 12th week of pregnancy. This means that the fetus develops under conditions of low oxygen during the first two months.

Blood circulation

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