Reduction-oxidation (redox) state regulation of matrix metalloproteinase activity in human fetal membranes

Article Abstract:

Antioxidants may be useful in preventing premature rupture of the membranes. During inflammation, levels of matrix metalloproteinases increase. These enzymes break down connective tissues. Free radicals can stimulate the production of these enzymes.

Health aspects, Physiological aspects, Fetal membranes, Antioxidants, Antioxidants (Nutrients), Oxidation-reduction reaction, Oxidation-reduction reactions

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Protective effect of N-acetylcysteine against fetal death and preterm labor induced by maternal inflammation

Article Abstract:

N-aetylcysteine (NAC) might protect unborn babies when the mother has an intrauterine infection, according to a study in mice. An intrauterine infection can cause the formation of free radicals, which can damage the baby. NAC inactivates free radicals. Intrauterine infections are believed to be one cause of premature birth.

Evaluation, Premature birth, Acetylcysteine

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Sonographic myometrial thickness predicts the latency interval of women with preterm premature rupture of the membranes and oligohydramnios

Article Abstract:

A study is conducted to hypothesize that a thickened myometrium at the time of preterm premature rapture of membranes (PPROM) predicts less myometrial wall stress and consequently a long latency interval. It is found that a significant thickening of the anterior and fundal walls of the uterus follows PPROM and also that thick myometrium in nonlaboring patients with PPROM is associated with longer latency interval.

United States, Science & research, Research, Usage, Ultrasound imaging, Diagnosis, Oligohydramnios

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