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Matrix metalloproteases and tumor invasion

Article Abstract:

The leading cause of death in patients with cancer is metastasis, a sequential process that allows cells to move from the primary tumor and grow elsewhere. It is reported that the matrix metalloproteases (MMPs) secreted by host fibroblasts promote tumor-cell invasion by activating a G-protein-coupled receptor.

Author: Arribas, Joaqiun
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United Kingdom, Analysis, Metastasis, Cancer metastasis

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Nonmyeloablative allogeneic immunotherapy for solid tumors

Article Abstract:

The advantages and advances in allogeneic hematopoietic stem cell transplantation are presented. The development and early clinical results of allogeneic stem cell transplantation as immunotherapy for solid tumors are discussed.

Author: Barrett, John, Childs, Richard W.
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2004
Stem cell transplantation, Graft versus host reaction, Graft vs. host disease

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Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas

Article Abstract:

The endothelial cells in 27 B-cell lymphomas are examined for cytogenetic alterations known to be present in the lymphoma cells. It suggests that microvascular endothelial cells in B-cell lymphomas are tumor related.

Author: Wagner, Oswald, Jager, Ulrich, Schwarzinger, Ilse, Streubel, Berthold, Chott, Andreas, Huber, Daniela, Exner, Markus
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Evaluation, Lymphomas, Cell research, Cytological research

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Subjects list: Care and treatment, Research, Tumors, Tumours
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