Medical Management of Aldosterone-Producing Adenomas

Article Abstract:

It seems possible to manage adenomas which affect aldosterone production and thereby control blood pressure. Adenomas are tumors which can influence glandular secretions such as aldosterone which regulates the sodium-potassium balance of the blood and therefore influences blood pressure. Following five years or more of medical treatment of 24 patients known to have aldosterone-producing adenomas, the average systolic blood pressure dropped from 175 mm Hg to 129 mm Hg, and diastolic pressure dropped from 106 mm Hg to 79 mm Hg. During that time, the concentration of potassium in the blood increased by nearly 50%.

Statistical Data Included, Management, Measurement, Physiological aspects, Blood pressure, Aldosterone assay, Adenoma, Blood pressure measurement, Potassium (Nutrient), Mineral metabolism, Aldosterone, Potassium metabolism

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The medical education of William Brooks Bigler (1863)

Article Abstract:

The notes of William Brooks Bigler, trained at Jefferson Medical College in Philadelphia, PA, in 1863, reveal the primitive state of medical knowledge in the 19th century. Medical education consisted primarily of lectures, with little clinical practice. Most of Bigler's training dealt with fevers. Quinine in the treatment of malaria is described, although the disease was poorly understood. Mercury purges, bloodletting, leeching, and other therapeutics are described. Bigler's writings indicate that most medical faculty members understood little more than their clinical colleagues.

History, Medical education

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