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Modulation of Abnormal Colonic Epithelial Cell Proliferation and Differentiation by Low-Fat Dairy Foods

Article Abstract:

Increasing the amount of calcium in the diet may reverse precancerous changes in the intestinal mucosa that could lead to cancer. These changes include altered growth patterns. Researchers randomly assigned 70 people with a history of intestinal polyps to a low-fat diet containing 1,200 milligrams of calcium per day or no dietary changes. During six and 12 months of treatment, colon biopsies revealed that patients on the high-calcium diet developed changes in the intestinal mucosa that were closer to normal cells. These changes were not seen in the patients on a regular diet.

Author: Yang, Kan, Fan, Kunhua, Halt, Peter R., Atillasoy, Evren O., Gilman, Jody, Guss, Janet, Moss, Steven F., Newmark, Harold
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
Cell proliferation, Diet therapy, High-calcium diet, High calcium diet

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Risk factors for advanced colonic neoplasia and hyperplastic polyps in asymptomatic individuals

Article Abstract:

Some dietary and lifestyle behaviors may increase a person's risk of developing colorectal cancer, according to a study of 3,121 people. A family history of colorectal cancer, smoking, and alcohol consumption were all risk factors for colorectal cancer. Those whose diet included cereal fiber and vitamin D had a lower risk of colorectal cancer, as did those who took non-steroidal anti-inflammatory drugs (NSAIDs). Body weight was not a risk factor.

Author: Lieberman, David A., Weiss, David G., Willett, Walter, Prindiville, Sheila
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003

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Magnesium intake in relation to risk of colorectal cancer in women

Article Abstract:

A population-based prospective study is conducted to evaluate the hypothesis that a high magnesium intake reduces the risk of colorectal cancer in women. The results indicate that a high magnesium intake might reduce the occurrence of colorectal cancer in women, and support potential benefits of increasing consumption of major foods contributing to magnesium intake in reducing colorectal cancer incidence.

Author: Wolk, Alicja, Bergkvist, Leif, Larsson, Susanna C.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Women

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Subjects list: Health aspects, Intestinal polyps, Risk factors, Colorectal cancer
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