Molecular epidemiology of HIV-1 infection in a small Brazilian County: Usefulness of envelope and polymerase sequences to epidemiologic studies

Article Abstract:

A genetic analysis of viral sequences from the small county of Miracema, Rio de Janeiro State is performed as the AIDS epidemic in Brazil is spreading from the large urban centers to small counties and the innermost parts of the country. The polyphyletic pattern suggests multiple viral introductions in the region while intracluster cases, including those with no known direct epidemiologic link, probably took part in the same chain of viral transmission.

Development and progression, Epidemics

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Improvements in survival among symptomatic AIDS patients by exposure category in Sao Paulo

Article Abstract:

The AIDS survival time per AIDS-case definition and exposure category in Sao Paulo State, Brazil during the periods 1992 to 1995 and 1998 to 2001 is assessed. It is attributable to the introduction of antiretroviral therapy with free universal access in 1996 and to diagnosis associated with the introduction in 1998.

Patient outcomes, Diagnosis, Control, Highly active antiretroviral therapy

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Trends of HIV infection among injection drug users in Brazil in the 1990s: the impact of changes in patterns of drug use

Article Abstract:

As the frequency of drug use in the Santos Metropolitan Region of Sao Paulo, Brazil, decreased between 1991 and 1999, so did the rate of HIV infection among intravenous drug addicts. However, during this time the use of crack cocaine increased from 11% of drug addicts in 1991 to 67% of drug addicts in 1999.

HIV infection, HIV infections, Drug addicts, Drug abusers, Drug use

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