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Mouse gene targeting: the cultural mouse

Article Abstract:

The author discusses the results of his research of the specifically targeted mouse mutations. He suggests that almost any specific genetic change can be generated, selected and verified now in culture before being converted to the germ lines of mice which helps to understand the mammalian genome physiology and human function in health and disease.

Author: Evans, Martin J.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001

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Mouse gene targeting:generating mice with targeted mutations

Article Abstract:

The author discusses the development of gene targeting in mice. The production of a specific mutation in a chosen gene in cultured mammalian cells and the transferring of this mutation to the mouse germ line has been carried out and reported.

Author: Capecchi, Mario R.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
United States, Cells (Biology), Cells

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Rapid anthrax test developed

Article Abstract:

Scientists at the Mayo Clinic have developed a PCR-based test to detect anthrax in human and environmental swab samples. The use of Roche's LightCycler machine helps to get positive results in less than 35 minutes.

Author: Cooney, Sarah
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Usage, Genetic aspects, DNA, Anthrax, Fluoroscopy

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Subjects list: United Kingdom, Analysis, Physiological aspects, Gene mutations, Gene mutation, Medical research, Genomes, Germ theory of disease, Germ theory (Medicine), Research
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