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Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

Article Abstract:

The most promising containment of immunodeficiency challenge infections was achieved by intradermal DNA prming followed by recombinant fowl pox virus booster immunizations in an 8-protocol comparison in rhesus macaques. Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations.

Author: Rizvi, Tahir A., Kalish, Marcia L., Robinson, Harriet L., Lifson, Jeffrey D., Montefiori, David C., Johnson, R. Paul, Hu, Shiu-Lok, Lu, Shan, Manson, Kelledy H., Mazzara, Gail P., Panicali, Dennis L., Herndon, James G., Glickman, Rhona, Candido, Maria A., Lydy, Shari I., Wyand, Michael S., McClure, Harold M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
United States, Viruses, Immunodeficiency

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Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I peptide with reduced CD8 binding

Article Abstract:

Research on a new method of immunomagnetic cell binding is presented. This method is developed to prevent T cells from binding to CD8 receptors by producing tetramers of human leukocyte antigens and peptides, and improving efficiency of tools for sorting specific human T cells in immunotherapy.

Author: Bodinier, Marie, Peyrat, Marie-Alix, Tournay, Claire, Davodeau, Francois, Romagne, Francois, Bonneville, Marc, Lang, Francois
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Peptides, HLA histocompatibility antigens, HLA antigens, CD8 lymphocytes, MHC antibodies

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MHC-I-restricted presentation of HIV-1 virion antigens without viral replication

Article Abstract:

Issues related to the role CD8 cytotoxic T lymphocytes play in combating viral infections are examined, focusing on the processes of dendritic cells, macrophages and MHC-1 molecules. Results provide insights into how anti-HIV cytotoxic T lymphocytes are activated.

Author: Buseyne, Florence, Le Gall, Sylvie, Boccaccio, Clair, Abastado, Jean-Pierre, Lifson, Jeffrey D., Arthur, Larry O., Riviere, Yves, Heard, Jean-Michael, Schwartz, Olivier
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Statistical Data Included, AIDS vaccines

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Subjects list: Research, Physiological aspects, France, T cells
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