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New options for the prevention of influenza

Article Abstract:

Neuraminidase inhibitors may be effective in preventing influenza. Neuraminidase is an enzyme that occurs on the surface of the virus and is involved in viral reproduction. It occurs on both influenza A and B virus. Drugs that block the action of this enzyme prevent the release of virus from infected cells. This would stop the virus from spreading to other cells. A 1999 study showed that a neuraminidase inhibitor called oseltamivir was effective in preventing influenza in healthy, non-vaccinated adults. It is possible that the virus will become resistant to these drugs and they may also be very expensive.

Author: Cox, Nancy J., Hughes, James M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Editorial, Prevention, Influenza, Enzyme inhibitors

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Probable person-to-person transmission of avian influenza A (H5N1)

Article Abstract:

A highly pathogenic avian influenza A (H5N1) virus caused poultry disease in 2004 in eight Asian countries infecting around 44 persons and killing 32 persons, most of them who had close contact with poultry. Possibility of person-to-person transmission in a family cluster of the disease in Thailand is investigated though no evidence of such transmission is reported.

Author: Dowell, Scott F., Cox, Nancy J., Zaki, Sherif R., Auwanit, Wattana, Ungchusak, Kumnuan, Auewarakul, Prasert, Kitphati, Rungrueng, Puthavathan, Pilaipan, Uiprasertkul, Mongkol, Boonnak, Kobporn, Pittayawonganon, Chakarat, Thawatsupha, Pranee, Chittaganpitch, Malinee, Khontong, Rotjana, Simmerman, James M., Chunsutthiwat, Supamit
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Thailand, Risk factors, Disease transmission, 2004 AD, Avian influenza

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Rocky Mountain spotted fever from an unexpected tick vector in Arizona

Article Abstract:

Rocky Mountain spotted fever is a life-threatening, tick-borne disease caused by Rickettsia rickettsii and a focus of Rocky Mountain spotted fever was investigated in rural eastern Arizona. The investigation documents the presence of Rocky Mountain spotted fever in eastern Arizona, with common brown dog ticks implicated as a vector of R. rickettsii.

Author: Swerdlow, David L., Cheek, James E., Zaki, Sherif R., Paddock, Christopher D., Demma, Linda J., Traeger, Marc S., Nicholson, William L., Blau, Dianna M., Singleton, Joseph, Jr., Levin, Michael L., Dasch, Gregory A., Eremeeva, Marina E., McQuiston, Jennifer H.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Science & research, Arizona, Research, Development and progression, Tick-borne diseases, Rocky Mountain spotted fever

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Subjects list: Health aspects
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