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Non-Hodgkin's lymphoma in childhood

Article Abstract:

Survival rates in children with non-Hodgkin's lymphoma have increased substantially in the past 30 years. Non-Hodgkin's lymphoma is a type of cancer that affects the B cells and T cells of the immune system. Most children develop tumors in their chest, abdomen or head and neck. Two-thirds of all children diagnosed with non-Hodgkin's lymphoma have advanced or metastatic disease. Chemotherapy is the mainstay of treatment for non-Hodgkin's lymphoma. Those with limited disease can often be cured with just 9 to 26 weeks of chemotherapy. Five-year survival rates in these children approach 95%. Children with advanced disease must be treated longer and their survival rates are lower. However, 75% of these children will also be cured. Children who relapse or never go into remission have a poor prognosis, but may be candidates for a bone marrow transplant. Unfortunately, many children develop diseases that are directly caused by the chemotherapy.

Author: Sandlund, John T., Crist, William M., Downing, James R.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
Care and treatment, Non-Hodgkin's lymphomas

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Radiotherapy for glioblastoma in the elderly

Article Abstract:

Trials conducted reveal that in elderly glioblasotma radiotherapy treatment with supportive cared had mild improvement in survival compared to supportive care alone. Radiotherapy did not have damaging effect on quality of life or cognitive function in the patients.

Author: Keime-Guibert, Florence, Chinot, Olivier, Taillandier, Luc, Cartalat-Carel, Stephanie, Frenay, Marc, Kantor, Guy, Guillamo, Jean-Sebastien, Jadaud, Eric, Colin, Philippe, Bondiau, Pierre-Yves, Menei, Philippe, Loiseau, Hugues, Bernier, Valerie, Honnorat, Jerome, Barrie, Maryline, Mokhtari, Karima, Mazeron, Jean-Jacques, Bissery, Anne, Delattre, Jean-Yves
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Usage, Drug therapy, Radiotherapy, Aged patients, Elderly patients, Glioblastoma multiforme, Clinical report

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