On the dialectic between molecular biology and integrative physiology: toward a new medical science

Article Abstract:

Molecular biology and integrative physiology each possess strong and weak points in explaining clinical dysfunction and disease. Molecular biology follows a linear approach in gaining knowledge about a disease while integrative physiology follows a feedback dependent or circular approach. At present, greater attention and funds are given to molecular biology because of its novelty and apparent cheapness in producing results. It is expected that future breakthroughs will arise from the interface friction between the two fields to focus on the true first causes of modern diseases.

Molecular biology, Physiology

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Observations on the gallic gastric illuminati

Article Abstract:

French physiologists, internists and surgeons have contributed much to the physiology of digestion and the therapeutic strategies for the diseases of stomach and duodenum. Rene Antoine Ferchault de Reaumur through the discovery of gastric acid and Jean Anthelme Brillat-Savarin through his essays on food and taste contributed to the knowledge of digestion and nutrition. The discoveries of Claude Bernard and Louis Pasteur provided a clear definition of gastric secretion. Renowned surgeons such as Guillaume Dupuytren introduced new concepts in the management of stomach conditions.

Reports, Digestion

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Death and the internal milieu: Claude Bernard and the origins of experimental medicine

Article Abstract:

The intimate link between death and physiology was central to Claude Bernard's ideology of biomedical science. His definition of experimental medicine was firmly grounded in the conception of an inanimate internal milieu. The mechanistic conditions of life, in this context, could be experimented upon and modified in deterministic ways. While Bernard's aim was to dominate nature, his biomedical paradigm of determinism was limited to the internal milieu. Bernard sought to extend the determinist limits of physiology in a bid to establish it as an independent science.

Beliefs, opinions and attitudes, Criticism and interpretation, Physiology, Experimental, Bernard, Claude

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