Outcomes of in-hospital ventricular fibrillation in children

Article Abstract:

The incidence of ventricular fibrillation or tachycardia among children is determined, while also examining whether the outcome is better for initial than for subsequent ventricular fibrillation or tachycardia. Results demonstrate that in pediatric patients with in-hospital cardiac arrests, survival outcomes were highest among patients in whom ventricular fibrillation or tachycardia was present initially than among those in whom it developed subsequently.

New England States, Causes of, Risk factors, Ventricular fibrillation, Tachycardia, New England, Cardiac arrest, Clinical report

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Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

Article Abstract:

A report on a family with a hereditary form of asymptomatic bradycardia associated with a mutation in the pacemaker-channel alpha-subunit HCN4 is presented. Functional analysis revealed that the mutant channels are activated at voltages more negative than those at which wild-type channels are activated, and hence, they supply less current during diastolic depolarization, resulting in slowing of the heart rate.

United States, Electromedical and Electrotherapeutic Apparatus Manufacturing, Electromedical equipment, Pacemakers, Usage, Diagnosis, Genetic aspects, Bradycardia, Pacemaker, Artificial (Heart)

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