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PET of brain amyloid and tau in mild cognitive impairment

Article Abstract:

A study used in vivo cerebral imaging of two abnormal protein aggregates, [beta]-amyloid and tau, to study persons with mild cognitive impairment or Alzheimer's disease. Results revealed that 2-(1-{6-[(2-[F-18] fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile-positron-emission tomography scanning can differentiate persons with mild cognitive impairment from those with Alzheimer's disease and those with no cognitive impairment.

Author: Thompson, Paul M., Bookheimer, Susan Y., Small, Gary W., Miller, Karen J., Vinters, Harry V., Kepe, Vladimir, Ercoli, Linda M., Siddarth, Prabha, Lavretsky, Helen, Burggren, Alison C., Cole, Greg M., S.-C. Huang
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
Diagnosis, PET imaging, Positron emission tomography, Clinical report

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Visualizing out-of-body experience in the brain

Article Abstract:

A case of a 63-year-old man suffering from tinnitus and implanted with paddle electrode over the superior temporal gyrus at the junction of the angular gyrus on the right side is presented. It is suggested that activation of angular and supramaginal gyrus junction changes multisensory integration.

Author: Dupont, Patrick, Ridder, Dirk De, van Laere, Koen, Menovsky, Tomas, van de Heyning, Paul
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Science & research, Psychological aspects, Care and treatment, Research, Case studies, Tinnitus, Self-perception, Electrodes, Self perception, Brain stimulation, Case study

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Patterns of brain activation in people at risk for Alzheimer's disease

Article Abstract:

In a study involving 30 subjects aged 47 to 82 years, patients with a gene associated with Alzheimer's disease exhibited alterations in the brain function with no perceptible behavioral changes suggesting that a base-line level of brain activation can be a predictor of subsequent memory decline.

Author: Bookheimer, Susan Y., Strojwas, Magdelena H., Cohen, Mark S., Saunders, Ann M., Strojwas, Magdalena H., Pericak-Vance, Margaret A., Mazziotta, John C., Small, Gary W.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Statistical Data Included, Genetic aspects, Apolipoproteins, Magnetic resonance imaging, Brain mapping

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Subjects list: Usage, Alzheimer's disease, United States
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