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Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

Article Abstract:

A randomized study is conducted on advanced non-small-cell lung cancer patients to investigate whether the addition of bevacizumab to paclitaxel and carboplatin improves survival in patients with metastatic non-squamous-cell, non-small-cell lung cancer. Result showed that the addition of bevacizumab to paclitaxel plus carboplatin in the treatment of selected patients with non-small-cell lung cancer has a significant survival benefit with the risk of increased treatment-related deaths.

Author: Gray, Robert, Perry, Michael C., Johnson, David H., Schiller, Joan H., Sandler, Alan, Brahmer, Julie, Dowlati, Afshin, Lilenbaum, Rogerio
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
Dosage and administration, Paclitaxel, Carboplatin, Bevacizumab

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Efficacy of gefitinib, and inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

Article Abstract:

The drug Iressa may improve symptoms and cause some tumor shrinkage in patients with non-small cell lung cancer, according to a study of 216 patients. Between one-third and one-half experienced an improvement in their symptoms, depending on which dose they received. In one-fifth of the patients, the drug caused the tumor to shrink at least 50%.

Author: Cella, David, Schiller, Joan H., Natale, Ronald B., Kay, Andrea C., Kris, Mark G., Herbst, Roy S., Lynch, Thomas J., Jr., Prager, Diane, Belani, Chandra P., Kelly, Karen, Spiridonidis, Harris, Sandler, Alan, Albain, Kathy S., Wolf, Michael K., Averbuch, Steven D., Ochs, Judith J.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Product information, Evaluation, Pharmaceutical industry, Product/Service Evaluation, AstraZeneca Pharmaceuticals L.P., Iressa (Medication)

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Lung cancer in U.S. women

Article Abstract:

In US women, lung cancer, caused by cigarette smoke, is the leading cause of cancer death. Cigarette smoking, its advertising and effects are discussed.

Author: Bach, Peter B., Kris, Mark G., Patel, Jyoti D.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Science & research, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Estrogen & Progestogen Preps, Health aspects, Research, Women, Risk factors, Smoking, Americans, Estrogen, Estrogens, Lung cancer

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Subjects list: Care and treatment, United States, Drug therapy, Lung cancer, Non-small cell, Non-small cell lung cancer
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