Postmenopausal hormones -- therapy for symptoms only
Article Abstract:
Hormone replacement therapy (HRT) should only be used to treat hot flashes and other symptoms of menopause. They should not be used to prevent heart disease, osteoporosis, or dementia. Studies have shown that HRT causes more harm than good for most postmenopausal women and does not improve their quality of life. Women should start with the lowest dose that will treat their symptoms and stop taking HRT once the symptoms stop completely.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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From presumed benefit to potential harm -- hormone therapy and heart disease
Article Abstract:
The story of hormone replacement therapy (HRT) and heart disease illustrates the dangers of promoting any medical treatment before it can be properly evaluated. Since the 1980s, doctors have recommended HRT based on observational studies that it might prevent heart disease. However, several large clinical trials in the late 1990s showed that HRT can actually increase the risk of heart disease.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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Hormone replacment therapy and cardiovascular diseases
Article Abstract:
Two studies published in 2003 which show that hormone replacement therapy may not prevent heart disease and may even cause it are probably correct even though they contradict studies published in 1985. The 1985 studies were both observational studies whereas the 2003 studies were both clinical trials. A well-designed clinical trial is usually more important than an observational study.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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