Pregnancy in patients with well-treated beta-thalassemia: outcome for mothers and newborn infants

Article Abstract:

Women with beta-thalassemia can have a baby if they have received treatment for the condition and have adequate heart function. Beta-thalassemia is a disorder of hemoglobin, a protein in red blood cells that carries oxygen. Women with thalassemia major were always told to avoid pregnancy. Researchers followed 19 women with beta-thalassemia who became pregnant either accidentally or intentionally. All had mild thalassemia or had been treated for thalassemia major for at least 10 years. All deliveries were normal, all the babies were healthy, and no woman developed heart complications as a result of pregnancy.

Prognosis, Thalassemia

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Neurofibromatosis type 1 with pregnancy-associated renovascular hypertension and the syndrome of hemolysis, elevated liver enzymes, and low platelets

Article Abstract:

A case is reported of a woman with neurofibromatosis who developed hypertension during pregnancy and other complications. Neurofibromatosis is a genetic disorder characterized partly by abnormalities in blood vessels. The 27-year-old woman developed hypertension during her first pregnancy, which can be a sign of preeclampsia. Laboratory tests revealed that she had the HELLP syndrome, which is characterized by red blood cell destruction, elevated liver enzymes and low blood platelet levels. X-rays of her kidneys after childbirth revealed renal artery stenosis.

Case studies, Preeclampsia, Neurofibromatosis

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