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Preoperative staging of non-small-cell lung cancer with positron-emission tomography

Article Abstract:

Positron-emission tomography (PET) appears to be more effective than CT imaging for detecting non-small-cell lung cancer that has spread to other parts of the body. This was the conclusion of a study of 102 patients with non-small-cell lung cancer. PET imaging was more accurate than CT imaging in detecting metastatic cancer and it detected metastatic cancer in 11 patients whose metastatic cancer had not been detected by other methods. Following PET imaging, 42 patients were diagnosed with more advanced cancer than their doctors had suspected, and 20 were diagnosed with less severe cancer.

Author: Pieterman, Remge M., Putten, John W.G. van, Meuzelaar, Jacobus J., Mooyaart, Eduard L., Vaalburg, Willem, Koeter, Gerard H., Fidler, Vaclav, Pruim, Jan, Groen, Harry J.M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Evaluation, PET imaging, Positron emission tomography

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Metabolic staging of lung cancer

Article Abstract:

Positron-emission tomography (PET) is a non-invasive technique that can detect cancer that has metastasized, or spread to other parts of the body. A study published in 2000 showed that PET imaging using (super 18)F-fluorodeoxyglucose could accurately identify non-small-cell lung cancer that has metastasized. This is possible because (super 18)F-fluorodeoxyglucose is metabolized more quickly in cancerous cells than in normal cells. However, (super 18)F-fluorodeoxyglucose also accumulates in areas of inflammation, which could cause a false-positive result.

Author: Berlangieri, Salvatore U., Scott, Andrew M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Equipment and supplies, Tumor staging, Cancer staging

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Improved tumor staging in colorectal cancer

Article Abstract:

Methods of detecting microscopic metastasis might identify cancer patients who would benefit from further treatment. A 1998 study showed that the polymerase chain reaction could be used to detect carcinoembryonic antigen in the lymph nodes from colorectal cancer patients. This would indicate that the patients had microscopic metastasis that cannot normally be detected by other means. Researchers have tried to detect microscopic metastasis in other tumors with little success.

Author: Lindblom, Annika
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
Colorectal cancer, Tumor markers

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Subjects list: Diagnosis, Development and progression, Metastasis, Cancer metastasis, Lung cancer, Non-small cell, Non-small cell lung cancer, Editorial
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