Prognosis of untreated patients with idiopathic membranous nephropathy

Article Abstract:

Idiopathic membranous nephropathy may go into remission if left untreated. This kidney inflammation is sometimes treated with immunosuppressive drugs or corticosteroids. Researchers followed 100 patients with idiopathic membranous nephropathy for 18 years, treating only the symptoms, such as hypertension and edema. During the first 36 months of follow-up, many patients experienced a reduction in kidney function followed by stabilization. Overall, the patients had an 88% chance of maintaining adequate kidney function after five years, and a 73% chance after eight years. After five years, two-thirds had experienced complete or partial remission. Fourteen patients eventually developed kidney failure that required regular dialysis. Women and those under 50 years old had the best prognosis.

Glomerulonephritis

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Pathophysiology of progressive nephropathies

Article Abstract:

The progression and incidence of various changes and breakdowns in systems of kidney disease is examined. for example, an injury to the kidney may make the glomerulus more permeable, allowing more plasma protein filtration, leading to the incidence of increased protein in the urine. This in turn may lead to setting in motion a sequence of events in which those proteins being filtered becoming damaging factors to the kidney itself. Methods of limiting protein filtration and measurements of various protein ratios can help interrupt the process and prevent scarring and failure.

Physiological aspects, Kidney diseases, Proteinuria

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Long-term outcome of renal transplant from older donors

Article Abstract:

A study to determine whether selecting older kidneys according to their histological characteristics before implantation would positively influence long-term outcome is presented. It is revealed that the long-term survival of the single or dual kidney from donors older than 60 years is excellent if the grafts are evaluated histologically before implantations.

New England States, Health aspects, Kidneys, Kidney transplantation, New England, Organ donors, Tissue donors

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