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Protective conditioning for acute graft-versus-host disease

Article Abstract:

Several patients suffering from lymphoid malignant diseases are conditioned with total lymphoid irradiation plus antithymocyte globulin followed by hematopoietic-cell transplantation. Observations reveal that the occurrence of severe graft-versus-host disease (GVHD) in humans as with mice is reduced with such a treatment.

Author: Bloch, Daniel A., Strober, Samuel, Negrin, Robert S., Blume, Karl G., Lowsky, Robert, Takahashi, Tsuyoshi, Dejbakhsh-Jones, Sussan, Laport, Ginna G., Hoppe, Richard T., Stockerl-Goldstein, Keith E., Johnston, Laura J., Grumet, F. Carl, Shizuru, Judith A., Yin Ping Liu
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Health aspects

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Protective conditioning for acute graft-versus-host disease

Article Abstract:

Several patients suffering from lymphoid malignant diseases are conditioned with total lymphoid irradiation plus antithymocyte globulin followed by hematopoietic-cell transplantation. Observations reveal that the occurrence of severe graft-versus-host disease (GVHD) in humans as with mice is reduced with such a treatment.

Author: Bloch, Daniel A., Strober, Samuel, Negrin, Robert S., Blume, Karl G., Lowsky, Robert, Takahashi, Tsuyoshi, Dejbakhsh-Jones, Sussan, Laport, Ginna G., Hoppe, Richard T., Stockerl-Goldstein, Keith E., Johnston, Laura J., Grumet, F. Carl, Shizuru, Judith A., Yin Ping Liu
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Risk factors, Globulin, Globulins, Hematopoietic growth factors

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Tolerance and chimerism after renal and hematopoietic-cell transplantation

Article Abstract:

Various new techniques for achieving tolerance and chimerism in a patient after the renal and hematopoietic-cell transplantation from a HLA-matched donor are discussed.

Author: Strober, Samuel, Benike, Claudia, Engleman, Edgar G., Lowsky, Robert, Dejbakhsh-Jones, Sussan, Hoppe, Richard T., Shizuru, Judith A., Scandling, John D., Busque, Stephan, Millan, Maria T.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2008
Evaluation, Patient outcomes, Causes of, Case study

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Subjects list: Care and treatment, Research, Hematopoietic stem cells, Hematopoietic stem cell transplantation, Graft versus host reaction, Graft vs. host disease, United States
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