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Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival

Article Abstract:

The clinical potential for expression of the gene encoding viral interleukin-10 (vIL-10) which was measurable in real time with positron emission tomography (PET) scanning is addressed by visualizing transplanted islets in the liver, the preferred clinical transplantation site. The results show that quantitative in vivo PET imaging is a valid method for facilitating the development of protocols for prolonging islet survival with the potential for tracking human transplants.

Author: Su-Jin Kim, Doudet, Doris J., Studenov, Andrei R., Nian, Cuilan, Ruth, Thomas J., Gambhir, Sanjiv Sam, McIntosh, Christopher H.S.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
Science & research, Health aspects, Research, Type 1 diabetes, Pancreatic beta cells, Pancreatic beta cell transplantation, Interleukin-10

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Positron emission tomography imaging for herpes virus infection: implications for oncolytic viral treatments of cancer

Article Abstract:

Positron emission tomography has proven to be an effective non-invasive modality for assessing the dissemination of viruses. Changes in thymidine kinase due to viral proliferation were detected 48 hours after injection of herpes simplex virus and for all .5 log increments.

Author: Bennett, Joseph J., Tjuvajev, Juri, Johnson, Paul, Doubrovin, Mikhail, Akhurst, Timothy, Malholtra, Sandeep, Hackman, Trevor, Balatoni, Julius, Finn, Ronald, Larson,Steven M., Federoff, Howard, Blasberg, Ronald, Fong, Yuman
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Canada, Statistical Data Included, Diagnosis, Cancer, Cancer treatment, Herpesvirus diseases, Herpesvirus infections

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PET concerns in bevacizumab treatment

Article Abstract:

The clinical and biological response to a single dose of bevacizumab in patients with rectal cancer was observed. Although researchers claim that the long-term results of combined therapy have been promising, PET found adverse effects on patients.

Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Complications and side effects, Colorectal cancer

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Subjects list: Care and treatment, United States, Usage, PET imaging, Positron emission tomography
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