Relationship between the calcium-to-protein ratio in milk and the urinary calcium excretion in healthy adults - a controlled crossover study

Article Abstract:

The incidence of osteoporosis among postmenopausal women has caused some experts to recommend increased calcium consumption in this group. However, there is some evidence that decreasing calcium excretion may, in fact, be more beneficial than increasing calcium consumption. Furthermore, since milk products are often recommended as a good source of dietary calcium, the effects of the other components of milk on the overall calcium balance must be taken into account. In particular, protein generally contributes to the excretion of calcium, presumably due to the fact that most animal proteins are somewhat acidic. In addition, the phosphorus content of milk may contribute to hyperparathyroidism, which affects calcium metabolism. For these reasons, a modified milk product was developed to provide an increased amount of calcium and a decreased protein content. The phosphorus content was also decreased, by about 9 percent. The total calcium content of the modified milk was 1,350 mg per 1,000 grams of milk (about one liter); conventional milk averages about 1,220 mg calcium. The protein content of the modified milk was reduced from 35 grams to 18.5 grams. In order to determine if the modified milk achieved its intended goal of reducing calcium excretion, it was tested on 55 volunteers in a crossover study. Each group drank either normal milk or high-calcium low-protein milk for three weeks, at which point the groups crossed over for three weeks of consuming the alternate product. The volunteers drinking the modified milk drank slightly less, so that the calcium consumption would be identical in both groups. The results showed that the product did indeed reduce calcium excretion in the urine by about 0.65 millimoles (26 milligrams) per day. While the study seems promising, it remains to be seen if this effect will aid postmenopausal women. The present study did not determine if the observed effect would persist over a long period of time. (Consumer Summary produced by Reliance Medical Information, Inc.)

Health aspects, Prevention, Physiological aspects, Food, Osteoporosis, Calcium, Calcium (Chemical element), Milk, High-calcium diet, High calcium diet

---

Intake, serum concentrations, and urinary excretion of manganese by adult males

Article Abstract:

Manganese is an essential nutrient for humans, but the exact requirement for this mineral is not known. Little research on manganese has been done with human subjects, partly because intake from the diet cannot be determined as the manganese content of most foods is unknown. There has been interest in this mineral recently because animal studies have suggested that manganese may affect both high-density-lipoprotein (HDL) cholesterol and bone density. However, findings in animal models may not apply to humans; further research is necessary with human subjects. Ten adult men were studied for 47 days during which time their food intake was analyzed for three days and their blood and urine levels of manganese were tested. The range of daily manganese intakes was 0.5 to 5.3 milligrams. Half of the time the subjects were obtaining less than the Estimated Safe and Adequate Daily Dietary Intake, which is similar to the RDA (Recommended Dietary Allowance) but is given for nutrients for which there is only incomplete data available. Blood manganese levels were not correlated with dietary intake, except at very high intakes. This suggests that blood levels may not be a good indicator of an individual's manganese status, and that other indicators are needed. (Consumer Summary produced by Reliance Medical Information, Inc.)

Standards, Measurement, Nutritional aspects, Manganese in human nutrition, Manganese (Nutrient)

---

Similar abstracts:

• Abstracts: Relationship between eating patterns meeting recommendations and subsequent mortality in 20 years. Serum leptin levels in alcoholic liver cirrhosis: relationship with gender, nutritional status, liver function and energy metabolism
• Abstracts: Associations between physical activity and physical fitness in American children
• Abstracts: Hypertension after renal transplantation in patients treated with cyclosporin and azathioprine. Polyvalent immune globulin and cytomegalovirus infection after renal transplantation
• Abstracts: Gonadotropin-releasing hormone deficiency in men: diagnosis and treatment with exogenous gonadotropin-releasing hormone
• Abstracts: The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.