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Respiratory Syncytial Virus and Premature Infants Born at 32 Weeks' Gestation or Earlier

Article Abstract:

Prophylactic treatment of premature infants born at 32 weeks or earlier to prevent respiratory syncytial virus (RSV) would be cost effective and save infant lives and sickness. With approval by the FDA of two drugs which provide a passive immunity, that is possible, although difficulties in cost and administration were such that the American Academy of Pediatrics felt compelled to issue risk-stratified guidelines for the use of them. The two drugs are Respigam which lowered risk of hospitalization from 41% to 63% in high-risk infants, and Palivizumab whichh lowered the risk by 55%.

Author: Stevens, Timothy P., Sinkin, Robert A., Hall, Caroline B., Maniscalco, William M., McConnochie, Kenneth M.
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 2000
Health aspects, Prevention, Drug therapy, Respiratory syncytial virus, Neonatal intensive care, Respigam (Medication)

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Lipid Intolerance in Neonates Receiving Dexamethasone for Bronchopulmonary Dysplasia

Article Abstract:

The corticosteroid dexamethasone may raise blood levels of a class of fats called triglycerides as well as levels of free fatty acids (FFA). Many premature babies need intravenous fats as a nutritional supplement after they are born. They may also need corticosteroids to prevent a complication of premature birth called bronchopulmonary dysplasia, which is a lung disease. In a study of 10 premature newborn babies who were receiving intravenous fats and dexamethasone to prevent bronchopulmonary dysplasia, six developed high blood levels of triglycerides and FFA.

Author: Sinkin, Robert A., Kendig, James W., Amin, Sanjiv B., McDermott, Michael P.
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 1999
Causes of, Complications and side effects, Physiological aspects, Infants (Premature), Premature infants, Hyperlipidemia, Dexamethasone

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How Commonly Are Children Hospitalized for Dehydration Eligible for Care in Alternative Settings?

Article Abstract:

Many children who are hospitalized for dehydration could be discharged to a short-stay treatment unit or even to their home for home nursing once the condition has been treated. In a study of 1,121 children hospitalized for dehydration, only 27% had a serious underlying problem. The rest had minimal dehydration and 95% were successfully treated within 24 hours. But many remained in the hospital longer than that. Eighty-six percent of the average hospital stay occurred after the child was successfully treated.

Author: McConnochie, Kenneth M., Conners, Gregory P., Lu, Esther, Wilson, Cole
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 1999
Care and treatment, Children, Hospitalization, Dehydration (Physiology)

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