Reversible membranous nephropathy associated with the use of nonsteroidal anti-inflammatory drugs

Article Abstract:

Use of over-the-counter non-steroidal anti-inflammatory drugs (NSAIDs) may be responsible for several cases of a kidney disease called membranous nephropathy. A review of 125 cases of this disease at two hospitals revealed that 13 patients had developed the disease while they were taking NSAIDs and the disease resolved when they stopped taking the drugs. The drugs included diclofenac, fenoprofen, ibuprofen, nabumetone, naproxen, and tolmetin. Physicians should get a careful drug history from people who present with the symptoms of this disease.

Causes of, Nonsteroidal anti-inflammatory drugs, Nonsteroidal anti-inflammatory agents, Nephrotic syndrome

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Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study

Article Abstract:

Continuing follow-up of the people who participated in the Diabetes Complications and Control Trial (DCCT) shows that the benefits of intensive insulin therapy last for up to seven or eight years. In the DCCT, some diabetic patients took insulin once a day, and others took insulin two or three times a day or more. Those who took multiple doses of insulin each day were less likely to develop diabetic kidney disease for up to eight years after the DCCT finished.

Prevention, Drug therapy, Type 1 diabetes, Diabetic nephropathies

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Prevention of contrast-induced nephropathy with sodium bicarbonate

Article Abstract:

The efficacy of sodium bicarbonate compared with sodium chloride for preventive hydration before and after radiographic contrast is examined. The results indicate that hydration with sodium bicarbonate before contrast exposure is more effective than hydration with sodium chloride for prophylaxis of contrast-induced renal failure.

United States, Science & research, Alkalies and chlorine, Alkalies and Chlorine Manufacturing, Sodium Bicarbonate, Health aspects, Care and treatment, Research, Kidney failure

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