Risk for subsequent cancer after diagnosis of basal-cell carcinoma: a population-based, epidemiologic study
Article Abstract:
Patients with basal-cell cancer, particularly younger patients, appear to be at greater risk for also developing other types of cancer. Researchers tracked 37,674 patients with basal-cell cancer up to 14 years after the cancer was first identified. Compared to the 3,245 expected cases of new cancers, there were 3,663 cases of new cancers in this population. This population was more likely to develop invasive skin cancer, non-Hodgkin lymph cancer, and cancer of the lip, throat, breast, and lung than a typical population. Risk for some cancers were higher if the basal-cell cancer was identified before age 60.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
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Syphilis and the risk of penis cancer
Article Abstract:
Syphilis infection does not appear to play a role in causing cancer of the penis. Before the discovery of the role of human papillomavirus, the virus that causes genital warts, syphilis was believed to be linked to penile cancer. Danish researchers used a cancer and a syphilis registry to compare percentages of patients with penile, colon, or stomach cancer who had prior diagnoses of syphilis. They found similar percentages in all three groups. It seems likely that syphilis patients were also more likely to contract human papilloma virus, which is also sexually transmitted.
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1996
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Basal-cell carcinoma of the skin: a harbinger of cutaneous and noncutaneous multiple primary cancer
Article Abstract:
A study that showed an increased risk for other cancers in patients with basal-cell skin cancer, particularly those identified earlier in life, should be interpreted with caution. Other factors that may explain this association include a genetic predisposition to cancer, increased sun or X-ray exposure, smoking history, toxic effects of previous cancer treatments, or more careful evaluation given the patients' cancer history. Infections with the human immunodeficiency virus may also partly explain the increased risk for non-Hodgkin lymphoma.
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1996
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