Risk of cancer in patients with gastric dysplasia: follow-up study of 67 patients

Article Abstract:

The expanding use of endoscopy has resulted in the diagnosis of many lesions of the stomach which may be termed ''precancerous.'' The precise risk of cancer among patients with such lesions, however, is controversial, and different authorities disagree on not only the risk, but the most appropriate course of action. To obtain further information on the relationship of the so-called precancerous lesions to the development of stomach cancer, 67 patients with moderate or severe gastric dysplasia (formation of abnormal tissue) originally observed prior to 1983 were followed-up. This follow-up included biopsy, in some cases gastrectomy (surgical removal of part of the stomach), and in one case autopsy. Of the 41 patients with moderate gastric dysplasia, regression was seen in 22, persistence was seen in 14, and progression to severe dysplasia occurred in three patients. Two patients progressed to stomach cancer. Of the 26 patients with severe gastric dysplasia, 12 patients regressed to moderate, mild, or no dysplasia; six showed no change on follow-up. A total eight patients progressed to stomach cancer. While the term 'dysplasia' is commonly used to refer to abnormal histological changes in tissue, there are rarely clear-cut definitions of what those changes are. It is clear that in many cases dysplasia is related to the development of cancer, but it is not clearly established that the cancer arises from the dysplasia. Although the observance of regression of dysplasia does not rule out a future progression to cancer, the authors believe that conservative treatment is appropriate for patients with gastric dysplasia, even if it is severe. Endoscopic or biopsy diagnosis of cancer should be obtained before aggressive steps like gastrectomy are undertaken. (Consumer Summary produced by Reliance Medical Information, Inc.)

Complications and side effects, Risk factors, Stomach cancer, Stomach, Dysplasia

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Racial Differences in Knowledge, Attitudes,and Cancer Screening Practices among a Triracial Rural Population

Article Abstract:

A study was conducted in Robeson County, North Carolina in which rural women over 40 were divided into racial groups whites, African Americans and Native Americans. They were surveyed to determine their knowledge, attitudes and behavior regarding breast and cervical cancer screening. All rural women experience barriers in receiving cancer screening but the barriers were greater for minority women, especially Native American.

United States, Health aspects, Usage, Demographic aspects, Beliefs, opinions and attitudes, Mammography, Rural women, Cancer screening

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