Safety, Immunogenicity, and Induction of Immunologic Memory by a Serogroup C Meningococcal Conjugate Vaccine in Infants: A Randomized Controlled Trial

Article Abstract:

A meningococcal C conjugate vaccine can protect babies from developing meningitis caused by Neisseria meningitidis. This bacterium is a common cause of meningitis in babies all over the world. In a study of 182 babies, one dose of the conjgate vaccine at 2, 3, and 4 months resulted in antibodies against the bacterium that persisted up to one year of age. The vaccine was well-tolerated and can be given with other vaccines.

Prevention, Pediatric diseases, Meningitis, Meningitis, Cerebrospinal, Bacterial vaccines, Meningococcal meningitis

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Antibody Concentration and Clinical Protection After Hib Conjugate Vaccination in the United Kingdom

Article Abstract:

It may not be necessary to give two-year-old children a booster shot of Hib vaccine if they received the first three doses as babies. In a study of 260 children who only received the first three doses, levels of protective antibodies decreased over time, but remained high enough until six years of age.

United Kingdom, Hib vaccines

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Immunogenicity and safety of a combination pneumococcal-meningococcal vaccine in infants: A randomized controlled trial

Article Abstract:

The safety and immunogenicity of a combination 9-valent pneumococcal-group C meningococcal conjugate candidate vaccine (Pnc9-MenC) administration as part of the routine UK infant immunization schedule at ages 2,3, and 4 months is determined. Results revealed that Pnc9-MenC combination vaccine administered to infants at ages 2,3, and 4 months demonstrated reduced group C meningococcal immunogenecity compared with MenC vaccine.

United States, Science & research, Health aspects, Research, Methods, Complications and side effects, Pneumococcal vaccine, Pneumococcal vaccines, Infants, Dosage and administration, Immunization, Immunogenetics, Immunization of infants

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