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Impact of antiretroviral treatment on AIDS dementia: a longitudinal prospective event-related potential study

Article Abstract:

Zidovudine may delay the progression of dementia in AIDS patients. Researchers used an eye examination called event-related potentials (ERP) to measure delays in reaction time in 98 HIV patients indicating possible intellectual deficits. About half of the patients were taking zidovudine and the rest received no treatment. The eye exam was given three times over a two-year period. Patients on zidovudine had faster reaction times than those receiving no treatment. This was true regardless of which stage of the infection the patient was in.

Author: Evers, Stefan, Grotemeyer, Karl-H., Reichelt, Doris, Luttmann, Susanne, Husstedt, Ingo-W.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1998
Evaluation, Prevention, Zidovudine, AIDS dementia, AIDS dementia complex

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Application of an expert system in the management of HIV-infected patients

Article Abstract:

An expert system that considers the genetic characteristics of the infecting virus may improve prescribing decisions in the treatment of patients with HIV infection. After the patient's HIV RNA sequence data are entered into the computer system, optimal drug regimens are recommended.

Author: Tilles, Jeremiah, Pazzani, Michael J., See, Darryl, Schroeder, Edison
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1997
United States, Health aspects, Statistical Data Included, Medicine, Information management, Expert systems, Dosage and administration, Antiviral agents

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Subjects list: HIV infection, Drug therapy, HIV infections
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