Saving the Vision of Children With Juvenile Rheumatoid Arthritis-Associated Uveitis

Article Abstract:

Uveitis potentially leading to blindness can develop in children with juvenile rheumatoid arthritis (JRA). Rheumatoid arthritis is an autoimmune inflammatory joint disease. Inflammation of the uvea, or vascular portion of the eye, may go undetected in children who do not notice slight changes in their vision. Ocular inflammation may develop in 89-24% of children with JRA, and 12% of children with uveitis may go blind. Topical corticosteroid drugs may be sufficient therapy, but oral corticosteroids and immunosuppressive drugs may be necessary. Comprehensive eye examination, including slit-lamp inspection, should be performed regularly in children with JRA.

Care and treatment, Causes of, Complications and side effects, Uveitis, Rheumatoid arthritis in children, Juvenile rheumatoid arthritis, Ocular manifestations of general diseases, Eye manifestations, Children, Blind, Blind children

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Prospects for Autoimmune Disease - Research Advances in Rheumatoid Arthritis

Article Abstract:

The treatment of rheumatoid arthritis has been advanced by the development of drugs that can actually modify the course of the disease rather than just treat the pain. One such treatment is drugs that block the activity of tumor necrosis factor, which is a naturally occurring inflammatory substance in the body.

Research, Rheumatoid arthritis

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Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: a randomized controlled trial

Article Abstract:

The drug methotrexate may not benefit people who have autoimmune inner ear disease, according to a study of 67 patients. This ear disease causes hearing loss that may be reversible if it is treated promptly. Many patients are treated with corticosteroid drugs.

Evaluation, Drug therapy, Autoimmune diseases, Hearing loss, Methotrexate

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