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Scientific and therapeutic advances in antiplatelet therapy

Article Abstract:

The platelet has emerged as a pivotal entity in cardiovascular diseases as the preeminescence of the platelet has spawned a variety of drugs, which is found to improve patient in acute coronary syndromes and percutaneous revascularization procedures. New insights at the cellular and genomic levels would probably generate novel drugs to inhibit platelet function more effectively.

Author: Topol, Eric J., Bhatt, Deepak L.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
Cardiovascular diseases, Drug therapy, Blood platelets, Platelet aggregation inhibitors

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Combination stroke therapy: Easy as APC?

Article Abstract:

Ischemic stroke caused by clotting of blood lodged in the brain that chokes off oxygen supply to critical tissue can be stopped from killing a person by administrating a clotbusting drug recombinant tPA only after 3 hours of stroke. This has many drawbacks as it has risky side effects such as hemorrhage, edema, and neurotomicity.

Author: Eng H Lo
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Causes of, Blood clotting, Blood coagulation, Protein C

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Accelerated transport and maturation of lysosomal alpha-galactoside A in Fabry lymphoblasts by an enzyme inhibitor

Article Abstract:

The authors report on tests of an inhibitor to prevent buildup of lipids in the hereditary metabolic disorder known as Fabry's disease. Unchecked, the lipid buildup can lead to kidney failure, heart attack, or stroke.

Author: Ishii, Satoshi, Fan, Jian-Qiang, Asano, Naoki, Suzuki, Yoshiyuki
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Research, Physiological aspects, Heart attack, Lipid metabolism, Acute renal failure, Acute kidney failure, Fabry's disease

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Subjects list: Health aspects, United States, Risk factors, Stroke (Disease), Stroke
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