Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran

Article Abstract:

The drug Exantra may be effective in preventing venous thromboembolism in patients who have experienced this condition in the past, according to a study of 1,233 patients. Exantra reduced the risk of a second episode of venous thromboembolism by about 85%. However, it may affect the liver adversely. Venous thromboembolism occurs when a blood clot forms, usually in the legs, and then travels to another part of the body.

Exantra (Medication)

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Ximelagatran vs low-molecular-weight heparin and warfarin for the treatment of systemic embolism

Article Abstract:

The study aimed to compare the efficacy and safety of ximelagatran with standard enoxaparin/warfarin treatment for the prevention of recurrent venous thromboembolism. It concluded that oral ximelagatran administered in a fixed dose without coagulation monitoring, was as effective as enoxaprin/warfarin for treatment of deep vein thrombosis with or without pulmonary embolism and showed similar low rates of bleeding.

United States, Drug therapy, Dosage and administration, Thrombosis, Deep vein, Deep vein thrombosis, ximelagatran (Medication)

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Comparison of ximelagatran with warfarin for the prevention of venous thromboembolism after total knee replacement

Article Abstract:

The drug Exanta may be better than warfarin in preventing abnormal blood clot formation after knee replacement surgery, according to a study of 1,851 patients. Both of these drugs are anticoagulants, but Exanta can be taken as a pill and patients do not need to be carefully monitored as they must be when taking warfarin. Exanta should be started the morning after the operation.

Exanta (Medication)

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