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Siblings, day-care attendance, and the risk of asthma and wheezing during childhood

Article Abstract:

Exposure to older siblings or other children in day-care centers during young childhood may reduce the incidence of asthma and wheezing in children aged 6 to 13 years. Researchers studied 1,035 children from birth to 13 years of age, and believe that early exposure to infectious diseases from other children may influence the developing immune system.

Author: Ball, Thomas M., Castro-Rodriguez, Jose A., Griffith, Kent A., Holberg, Catharine J., Martinez, Fernando D., Wright, Anne L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
United States, Statistical Data Included, Causes of, Children, Environmental aspects, Communicable diseases, Child health

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Asthma and wheezing in the first six years of life

Article Abstract:

Wheezing in infants may have some predictive value for a later diagnosis of asthma. A population-based study of 1246 newborns in Tucson, Arizona assessed the infants throughout the first six years of life. Wheezing in the first three years of life was not thought to correlate with diminished lung function or asthma later in life. Sixty percent of children who wheezed in the first three years had stopped by the time they were six. Transient early wheezing was distinguished from persistent wheezing, with the latter being more likely to indicate development of asthma by age six. Infants with persistent wheezing were more likely to have an elevated serum immunoglobulin E (IgE) level at nine months of age which indicates asthma and allergies. These infants had much lower lung function at age six, indicating a deterioration in airway function. Infants of mothers who smoked had higher rates of transient early wheezing.

Author: Holberg, Catharine J., Martinez, Fernando D., Wright, Anne L., Halonen, Marilyn, Morgan, Wayne J., Taussig, Lynn M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
Complications and side effects

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Relationship of infant feeding to recurrent wheezing at age 6 years

Article Abstract:

Breastfeeding appears to decrease the risk of recurrent wheezing among nonallergic children. Researchers used parental surveys and physician reports to study the relationship between the feeding practices of 988 newborns and wheezing six years later. Approximately 11% of the children who were bottlefed and 6.6% of those who received some breast milk had recurrent wheezing. The protective effect of breast milk was significant only in the children who did not suffer from allergies. Approximately 11% of recurrent wheezing in nonallergic children could be attributed to not breast feeding. Nonallergic children who were not breastfed were approximately three times as likely to wheeze as other nonallergic children independent of lower respiratory tract infections during infancy, maternal education, maternal hay fever, and ethnic background.

Author: Holberg, Catharine J., Martinez, Fernando D., Wright, Anne L., Taussig, Lynn M.
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 1995
Risk factors, Food and nutrition, Infants, Breast feeding

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Subjects list: Health aspects, Development and progression, Asthma in children, Childhood asthma, Wheeze, Wheezing
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