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Simian LCV infection in humans unlikely to cause malignant proliferation

Article Abstract:

Malignant proliferation of human B cells is not likely to be caused by simian infections in humans, while simian B cells transmitted to humans following xenotransplantation are unlikely to be immortalized by Epstein Barr virus. These were indicated by findings from a study conducted by Amir Moghaddam and colleagues at Harvard Medical School in Boston, MA. Results showed species restriction to efficient B-cell immortalization, as lymphocryptoviruses may not be able to efficiently immortalize B cells from more distantly related species.

Author: Clark, Cathy
Publisher: NewsRX
Publication Name: World Disease Weekly Plus
Subject: Health
ISSN:
Year: 1998
Disease transmission, B cells, Epstein-Barr virus, Simian viruses

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Blood supply probably is safe from risk of CJD

Article Abstract:

Results of a study conducted by Bruce Evatt and his colleagues at the US Centers for Disease Control and Prevention (CDC) indicated that Creutzfeldt-Jakob disease could not be trasnmitted through the transfusion of donated blood. The researchers studies specimens from decedents supporting genetic bleeding disorders and analyzed slides prepared at the CDC. They also evaluated formalin-fixed paraffin block brain samples from patients who died from hemophilia.

Author: Clark, Cathy
Publisher: NewsRX
Publication Name: World Disease Weekly Plus
Subject: Health
ISSN:
Year: 1998
Hemophilia, Creutzfeldt-Jakob disease, Blood transfusion, Evatt, Bruce

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PCR method detects T. cruzi in blood

Article Abstract:

Studies conducted by researchers at Argentina's Universidad Nacional de Cordoba indicated the possible use of DNA amplification by using polymerase chain reaction in detecting the presence of Trypanosoma cruzi in the blood. Trypanosoma cruzi is the pathogen causing Chagas disease. The method could be used as an alternative for serological tests and direct detection of parasites in the blood which lack specificity and sensitivity to T. cruzi.

Author: Clark, Cathy
Publisher: NewsRX
Publication Name: World Disease Weekly Plus
Subject: Health
ISSN:
Year: 1998
Diagnosis, Polymerase chain reaction, Chagas' disease, Chagas disease

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Subjects list: Research
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