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Sirolimus-eluting stents vs vascular brachytherapy for in-stent restenosis within bare-metal stents

Article Abstract:

A trial was conducted to compare the use of vascular brachytherapy with implantation of the sirolimus-eluting stent for the treatment of restenosis occurring within a previously placed bare-metal stent. Results revealed that superior clinical and angiographic outcomes were obtained from the use of sirolimus-eluting stents as compared to treating restenosis within a bare-metal stent with vascular brachytherapy.

Author: Holmes, David R., Kuntz, Richard E., Hong Wang, Satler, Lowell, Teirstein, Paul, Sketch, Michael, O'Malley, James, Caramanica, Eileen, Cohen, Sidney A., Popma, Jeffery J.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Sirolimus

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Brachytherapy for in-stent restenosis: A distant second choice to drug-eluting stent placement

Article Abstract:

In-stent restenotic lesions are an important clinical problem and of the numerous modalities used to treat them till date, vascular brachytherapy has been the most effective. Some concerns however about brachytherapy including safety of radiation therapy have led to trials of other therapies and of these drug-eluting stents appear to be the most acceptable.

Author: Moliterno, David J., Mukherjee, Debabrata
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Care and treatment, Coronary stenosis

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Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke

Article Abstract:

The role of carotid plaque rupture and thrombosis in ischemic stroke pathogenesis in patients undergoing carotid endarterectomy is examined. A major role of carotid thrombosis and inflammation in ischemic stroke in patients affected by carotid atherosclerotic disease is demonstrated.

Author: Holmes, David R., Schwartz, Robert S., Spagnoli, Luigi Giusto, Sangiorgi, Giuseppe, Pistolese, Raimondo, Mauriello, Alessandro, Bonanno, Elena, Fratoni, Stefano, Pipegras, David G., Ippoliti, Arnold
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Science & research, Research, Risk factors, Stroke (Disease), Stroke, Stroke patients, Endarterectomy

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Subjects list: Health aspects, United States, Complications and side effects, Clinical trials, Comparative analysis, Stent (Surgery), Stents, Radioisotope brachytherapy, Brachytherapy
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