Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents

Article Abstract:

The long-term outcome of treatment with sirolimus-eluting stents, as compared with bare-metal stents is evaluated by analyzing the data obtained from randomized trials. The results have shown that the use of sirolimus-eluting stents have no significant effect on overall long-term survival and survival free of myocardial infarction, as compared with bare-metal stents, but the risk of stent thrombosis is at least as great as that observed with bare-metal stents.

Analysis, Risk factors, Heart attack, Thrombosis, Blood clot, Clinical report

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Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: A randomized controlled trial

Article Abstract:

An attempt is made to assess whether drug-eluting stents are more effective treatment of in-stent restenosis as compared to conventional balloon angioplasty and to examine the relative merits of a sirolimus-eluting stent and a paclitaxel-eluting stent. The findings indicate that a strategy based on sirolimus or paclitaxel-eluting stents is superior to conventional balloon angioplasty for the prevention of recurrent restenosis.

Science & research, Research

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Sirolimus-eluting stents vs paclitaxel-eluting stents in patients with coronary artery disease: Meta-analysis of randomized trials

Article Abstract:

An attempt is made to compare outcomes of sirolimus-eluting and paclitaxel-eluting coronary stents on the basis of data generated by randomized head-to-head clinical trials. It is concluded that patients receiving sirolimus-eluting stents had a significantly lower risk of restenosis and target vessel revascularization compared with those receiving paclitaxel-eluting stents.

Comparative analysis, Cardiovascular instruments, Implanted, Cardiovascular implants, Cardiac patients, Paclitaxel

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