Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients

Article Abstract:

A study is designed to show noninferiority of the paclitaxel stent as compared with the sirolimus stent, defined as a difference in the extent of in-segment late luminal loss of no more than 0.16 mm. The results reveal that in patients with diabetes mellitus and coronary artery disease, use of the sirolimus-eluting stent is associated with a decrease in the extent of late luminal loss, as compared with use of the paclitaxel-eluting stent, suggesting a reduced risk of restenosis.

United Kingdom, Diabetes, Diabetes mellitus, Dosage and administration, Paclitaxel

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Early administration of reteplase plus abciximab vs abciximab alone in patients with acute myocardial infarction referred for percutaneous coronary intervention

Article Abstract:

The optimal pharmacological strategy for bridging the delay between admission and performance of percutaneous coronary intervention (PCI) in patients with acute myocardial infraction (MI) is not known. Various studies show that early administration of reteplase plus abciximab does not lead to a reduction of infarct size compared with abciximab alone in patients with acute MI referred for PCI.

Influence, Heart attack

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A clinical trial of abciximab in elective percutaneous coronary intervention after pretreatment with clopidogrel

Article Abstract:

The drug abciximab does not appear to benefit patients who have angioplasty to treat coronary artery disease, according to a study of 2,159 patients. Angioplasty is a procedure that opens blocked arteries. In this study, those who took abciximab had the same outcome as those who took a placebo, or inactive substance.

Care and treatment, Evaluation

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