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HDL cholesterol predicts coronary heart disease mortality in older persons

Article Abstract:

Low levels of high density lipoprotein cholesterol (HDL-C) appear to increase the risk of death from coronary heart disease (CHD) in older people. Between 1987 and 1989, researchers interviewed and took blood samples from 3,904 people who were at least 71 years of age. After a median follow-up period of 4.4 years, people with low HDL-C levels were 2.5 times more likely to die from CHD than people with higher HDL-C levels, independent of other CHD risk factors. Compared to their same gender counterparts with higher HDL-C levels, men with low HDL-C were nearly five times more likely to die of CHD and women with low HDL-C were twice as likely to die of CHD. Low HDL-C increased the risk of chest pain, heart attacks, or sudden death among men and women with no history of a heart attack or recent CHD hospitalization. High total cholesterol levels were associated with an increased risk of death from CHD in women, but not in men.

Author: Hennekens, Charles H., Guralnik, Jack M., Wallace, Robert B., Glynn, Robert J., Salive, Marcel E., Corti, Maria-Chiara, Havlik, Richard J., Harris, Tamara, Seeman, Teresa E., Berkman, Lisa F., Field, Terry S.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
Health aspects, Aged, Elderly, Coronary heart disease, Cholesterol, HDL, HDL cholesterol lipoproteins, Blood cholesterol

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Effect of estrogen therapy on gallbladder disease

Article Abstract:

A study conducted to determine the effect of estrogen therapy in healthy postmenopausal women on gallbladder disease outcomes is reported. The results suggest an increase in risk of biliary tract disease among postmenopausal women using estrogen therapy.

Author: LaCroix, Andrea Z., Greenland, Philip, Wallace, Robert B., Rodabough, Rebecca J., Cirillo, Dominic J., Larson, Joseph C., Limacher, Marian C.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Influence, Drug therapy, Gallbladder diseases, Postmenopausal women, Estrogen, Estrogen antagonists

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Subjects list: Risk factors
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