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Staphylococcus aureus With Reduced Susceptibility to Vancomycin--Illinois, 1999

Article Abstract:

The fourth known US case of Staphylococcus aureus infection that was partially resistant to the antibiotic vancomycin is described. This bacterium is the most common cause of hospital- and community-acquired infections. The 63-year-old woman had a strain of Staphylococcus aureus that was resistant to penicillin, oxacillin, clindamycin, erythromycin, ciprofloxacin, and rifampin but susceptible to trimethoprim-sulfamethoxazole, tetracycline, and gentamicin. Despite treatment with intravenous vancomycin, rifampin, and tobramycin, she patient died of endocarditis, a bacterial infection in the heart. If Staphylococcus aureus becomes completely resistant to vancomycin, there will be few drugs left to treat the infection.

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000

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Worry grows as antibiotic-resistant bacteria continue to gain ground

Article Abstract:

Researchers discussed the emergence of antibiotic-resistance in bacteria at the 1997 meeting of the American Society for Microbiology. In 1997, reports of vancomycin resistance in Staphylococcus aureus were published. This would mean that there are no effective antibiotics to treat serious infections with this bacterium. This resistance appears rare so far, but the bacterium could pass the gene for vancomycin resistance to other bacteria. The SENTRY Antimicrobial Surveillance project consists of 68 medical centers worldwide who actively monitor bacterial resistance to over 70 different antibiotics.

Author: Stephenson, Joan
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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Update: Staphylococcus aureus with reduced susceptibility to vancomycin - United States, 1997(From the Centers for Disease Control and Prevention)

Article Abstract:

Hospitals in the US should be on the lookout for strains of Staphylococcus aureus that have reduced susceptibility to vancomycin. Since the bacterium became resistant to methicillin in the 1980's, vancomycin has been used for serious infections. In July and August, 1997, two patients became infected with a strain of the bacterium that was not completely susceptible to vancomycin. One patient resided in Michigan and the other in New Jersey. The bacterium was susceptible to other antibiotics and both patients were successfully treated.

Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997

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Subjects list: Health aspects, Case studies, Staphylococcus aureus, Drug resistance in microorganisms, Vancomycin, Microbial drug resistance
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