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Tailoring arthritis therapy in the wake of the NSAID crisis

Article Abstract:

The recent trial of celecoxib suggests that it increases cardiovascular risk and indicates that it may slow the growth of colon polyps, which would reduce the patient's risk of colon cancer. The benefit achieved from arthritis treatment must be weighed against the risks of adverse events that are likely to be encountered with traditional nonsteroidal antiinflammatory drugs (NSAIDs) and coxibs.

Author: Olsen, Nancy J.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United Kingdom, Drug therapy, Nonsteroidal anti-inflammatory drugs, Nonsteroidal anti-inflammatory agents, Arthritis, Dosage and administration

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Mevalonate Kinase deficiency and autoinflammatory disorders

Article Abstract:

The diverse clinical manifestations and related long term effects due to the deficiency of enzyme Mevalonate Kinase, is discussed.

Author: Haas, Dorothea, Hoffmann, Georg F.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Health aspects, Deficiency diseases, Disease/Disorder overview, Mevalonate

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Subjects list: Cardiovascular diseases, Risk factors
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