The TRAIL to selective tumor death

Article Abstract:

The authors discuss historical discoveries concerning the tumor necrosis factor, a cytokine always hoped to be a useful cancer fighter. The most recent discovery indicates that researchers may have found a cytokine with the proper effect and without the heretofore unacceptable toxicity to the system.

Health aspects, Statistical Data Included, Cytokines

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Monclonal antibody therapies -- a 'constant' threat to cancer

Article Abstract:

Research shows that monoclonal antibodies may act through different mechanisms when used as antineoplastic agents. In some cases, the Fc portion activates the immune system when it binds to various Fc receptors. But other effects are independent of Fc receptor binding.

Monoclonal antibodies

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How the immune system puts the brain to sleep

Article Abstract:

Tumor necrosis factor, a mediator of inflammation, prevents the degradation of RGS7, a component of the G protein complex. G protein signaling is one mechanism of signal transduction in the brain. Elevated levels of TNF in the brain cause hypomotility and sleep.

G proteins

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