The analgesic efficacy of intramuscular parecoxib sodium in postoperative dental pain

Article Abstract:

A study of the efficacy of lower doses of COX, -2 selective inhibitor parecoxib sodium for intravenous (IV) or intramuscular (IM) administration in postoperative dental pain is presented. The results show that parecoxib 20 mg IM is an effective and rapidly acting analgesic dose in patients who have undergone dental surgery and is a useful alternative to the higher 40 mg IV/IM dose or a 30 mg IV/IM dose of ketorolac in patients undergoing dental surgery.

Oral surgery, Pain, Postoperative, Postoperative pain

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The optimal analgesic dose of rofecoxib: overview of six randomized controlled trials

Article Abstract:

A single dose of 50 milligrams of rofecoxib is effective in treating postoperative pain following dental surgery. This was the conclusion of researchers who evaluated dosages ranging from 7.5 milligrams to 500 milligrams. Rofecoxib belongs to a class of drugs called COX-2 inhibitors.

Drug therapy, Rofecoxib

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The use of COX-2 inhibitors for acute dental pain: a second look

Article Abstract:

Cyclo-oxygenase-2 inhibitors (COX-2) have been prescribed as first-line agents for the treatment of dental pain. However, literature shows its adverse reactions tend to cause cardiovascular diseases. A reappraisal on the usage of these drugs is recommended.

Evaluation, Complications and side effects

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